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Supporting Research for CardioMetaboliQ Indexes & Biomarkers

For decades, LDL cholesterol has been the primary focus in cardiovascular health..and A1C in metabolic health. The research now clearly supports new, more representative indicators, like TyG, FLI, AIP, RC…following is selected research that supports a new paradigm in cardiometabolic risk assessment.

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93.2% Not In Optimal Cardiometabolic Health 2018 Survey

US Survey of 55,000 adults indicating just 6.8% were in optimal cardiometabolic health.

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Remnant Cholesterol Superior to ApoB for New Onset ASCVD

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Triglyceride-Glucose WHtR Best for Atherosclerosis

15 year study following 95,000+ subjects comparing various TyG index variants.

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Remnant Cholesterol Reveals Residual Risk with Statins

In patients that are “well controlled” on statin medications, with LDL Cholesterol at or below 70 mg/dl, Remnant Cholesterol can reveal residual risk of heart disease.

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Fatty Liver and Heart Disease Risk in Young People

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Remnant Cholesterol Superior to ApoB for Atheroma Growth

In patients with diagnosed coronary artery disease, on treatment with statins, Remnant Cholesterol proved superior to ApoB and LDL in predicting risk of progression of atheroma.

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Fatty Liver and Heart Disease Risk in Young People

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Triglyceride-Glucose-WHtR Cumulative Level and CVD 2024

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Triglyceride-Glucose Index (TyG) Superior to HOMA-IR 2024

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Atherogenic Index Superior to Traditional CVD Risk Markers

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Fatty Liver Increases All Cause Mortality

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Triglyceride-Glucose Index and Alzheimer’s Risk

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Remnant Cholesterol >39 Doubles Mortality vs <19

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Triglyceride-Glucose Index and Breast Cancer Risk

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Fatty Liver Reduces Brain Size & Affects Cognitive Function

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Remnant Cholesterol Superior to LDL for Diabetes Risk

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Remnant Cholesterol and 10 Year Diabetes Risk

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TyG-Waist/Height Ratio Predicts CV, T2DM, Death in MetS

Triglyceride-Glucose Index-Waist-Height Ratio Predicts Risk of Cardiovascular Disease, Diabetes and Mortality in Metabolic Syndrome.

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Atherogenic Index Predictive of Stroke over 0.12

In patients followed for over 8 years in their late 50’s, an Atherogenic Index over 0.12 increased first stroke risk by 35-84%.

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